mavorixafor will raise the amount or result of codeine by influencing hepatic enzyme CYP2D6 metabolism. Contraindicated. Mavorixafor (a powerful CYP2D6 inhibitor) is contraindicated with medicines that are very dependent on CYP2D6 for clearance.Intense Allergic Reactions. Dextromethorphan could cause allergic reactions, that may be major. End usin